Nanobiotix's updated Phase 1 data for JNJ-1900 (NBTXR3) in inoperable, locoregionally recurrent NSCLC show no dose-limiting toxicities and a feasible intratumoral injection, with one-year results of 79% locoregional control, 61% LPFS, and 70% OS achieved at a lower re-irradiation dose. The findings reinforce the hafnium oxide nanoparticle–based radiosensitizer's potential to enable safe retreatment and spur further enrollment in dose-escalation and expansion cohorts.

Health· Sep 14, 2026

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Nanobiotix· Health · 6 sources · Sep 14, 2026Story

Nanobiotix Reports 79% Locoregional Control in Recurrent Lung Cancer Trial

Health· Sep 14, 2026

Facts from Wikidata (CC0). Image by Nanobiotix via Wikimedia Commons (Public domain).

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About Nanobiotix

Nanobiotix es una empresa de biotecnología que utiliza la nanomedicina para desarrollar nuevas técnicas de radioterapia para pacientes con cáncer. La empresa tiene su sede en París, con oficinas corporativas adicionales en Nueva York y Massachusetts.

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Country: France
Headquarters: Paris
Inception: 2003
Website: http://nanobiotix.com/

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