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Sam Hay

chemist

Sam Hay

Químico de Nueva Zelanda

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About Sam Hay

Sam Hay es un químico de Nueva Zelanda y un Profesor de Química Biofísica en el Departamento de Química y el Instituto de Biotecnología de Manchester (MIB) en la Universidad de Manchester. Su investigación en general se basa en la química computacional y la química teórica, específicamente en las áreas de In silico Enzymology, roles de la mecánica cuántica en procesos biológicos, modelado cinético de reacciones complejas y espectroscopia de alta presión.

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Occupation: chemist, university teacher

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Good vibrations in enzyme-catalysed reactions Reductive dehalogenase structure suggests a mechanism for B12-dependent dehalogenation New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition.UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis Fast protein motions are coupled to enzyme H-transfer reactions Evidence to support the hypothesis that promoting vibrations enhance the rate of an enzyme catalyzed H-tunneling reaction Promoting motions in enzyme catalysis probed by pressure studies of kinetic isotope effects Direct analysis of donor-acceptor distance and relationship to isotope effects and the force constant for barrier compression in enzymatic H-tunneling reactions University of Manchester Stockholm University

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