2018-present: Primero Soy Mexicana and Mexicana Enamorada
On March 2, 2018, Aguilar released her first solo album, Primero Soy Mexicana, produced by her father, Pepe. The album featured eleven well-known ranchera songs previously performed by other prominent music artists, such as Lucha Villa, Rocío Dúrcal, and her grandmother, Flor Silvestre. Aguilar performed the album's first single, "Tu Sangre en Mi Cuerpo" at the 2018 Premios Tu Mundo. On September 20, Aguilar was nominated for Best New Artist, and her album, Primero Soy Mexicana was nominated for Best Ranchero/Mariachi Album at the 19th Annual Latin Grammy Awards. At the ceremony, she performed "La Llorona", where she received a standing ovation from the audience. Aguilar received widespread praise from various artists, including Mexican ranchera singer Vicente Fernández for her performance. On December 7, Aguilar's album Primero Soy Mexicana, was nominated for a Grammy Award for Best Regional Mexican Music Album.
On April 3, 2019, Aguilar was named the Artistic and Cultural Ambassador of Zacatecas, Mexico by Mayor Ulises Mejía Haro. On May 21, Aguilar was nominated for three awards at the 2019 Premios Juventud. She performed a medley of songs alongside mariachi singers Christian Nodal and Pipe Bueno. On July 23, Aguilar released an exclusive cover performance of "Shallow" on the Recording Academy's YouTube page, with permission from its songwriter, Lady Gaga. It was the first time that Aguilar recorded music in English.
On January 31, 2020, Aguilar released a tribute EP to American singer, Selena, titled Baila Esta Cumbia. On September 24, 2021, she released her second solo album, Mexicana Enamorada. On April 1, she released "En Realidad", the first single from her third solo studio album.