Overview
Anna of Savoy, born Giovanna (1306–1365), was a Byzantine Empress consort, as the second spouse of Andronikos III Palaiologos. She served as regent, with the titles augusta and autokratorissa, during the minority of her son John V Palaiologos from 1341 until 1347. In Byzantium, she was known as Anna Palaiologina, owing to her marriage to Andronikos.
Life
Anna was a daughter of Amadeus V, Count of Savoy, and his second wife, Maria of Brabant. She was betrothed to Andronikos III Palaiologos in September 1325, during which time he was involved in a civil war with his paternal grandfather Andronikos II Palaiologos.
The marriage took place in October 1326. She joined the Eastern Orthodox Church and took the name Anna. In 1328, Andronikos III entered Constantinople and finally deposed his grandfather.
Regent
On 14-15 June 1341, Andronikos III died. He was succeeded by their son John V who was still three days short of his ninth birthday. Anna was appointed regent for her son. However, Andronikos III had entrusted the administration to his advisor John Kantakouzenos, whom Anna did not trust.
From Wikipedia (CC BY-SA 4.0).