Avedon is a surname. Notable people with the surname include:
Barbara Avedon (20th century), American television writer
Doe Avedon (1925–2011), American model
Loren Avedon (born 1962), American actor & martial artist
Gregg Avedon (born 1965), American model
Michael Avedon (born 1991), American photographer
Richard Avedon (1923–2004), American photographer