Characters
Saya Kisaragi (更衣 小夜, Kisaragi Saya): The main protagonist—she is unrelated to any previous entry in the Blood franchise aside from her first name, chosen weapon and abilities. Outwardly, Saya is an innocent and clumsy girl who acts as a shrine maiden at her father's shrine, going out at night to hunt Elder Bairns as part of a sworn duty. In reality, she is an Elder Bairn who was abandoned and raised by humans. Due to an oath she swore, she is unable to feed on humans herself, and the experiment was designed to see if her nature could be altered. Saya is voiced by Nana Mizuki in Japanese. Mizuki described Saya as she is portrayed in the anime as an easygoing girl who enjoys her school life and shares a strong bond with Tadayoshi. In the English dub, she is voiced by Alexis Tipton.
Tadayoshi Kisaragi (更衣 唯芳, Kisaragi Tadayoshi): Saya's father, and the owner of the Shinto shrine where Saya acts as shrine maiden. He also supervises her role as a slayer of Elder Bairns. In truth, he is a human-Elder Bairn hybrid used by Fumito to capture and manipulate Saya due to their strong similarity. Tadayoshi is voiced in Japanese by Keiji Fujiwara. Fujiwara described Tadayoshi as a stern character who hides the depths of his fatherly feelings for Saya. In the English dub, he is voiced by Bill Jenkins.
Fumito Nanahara (七原 文人, Nanahara Fumito): The owner of a cafe just opposite Saya's home, who acts as cook for Saya and her father, preparing Saya's school lunches. Fumito is revealed to the mastermind behind the entire experiment and the main antagonist, manipulating events in an attempt to rewrite who Saya is. Fumito is voiced in Japanese by Kenji Nojima. Nojima described Fumito's character as a mysterious, friendly and knowledgeable figure. In the English dub, he is voiced by Robert McCollum.
Yūka Amino (網埜 優花, Amino Yūka): A member of Saya's class who acts as an older sister figure, chastising Saya for being late or distracted while also caring about her. In reality, Yūka is an ally of Fumito who joins his experiment in exchange for political power in Tokyo. She is the only member of the "main cast" to survive. Yūka was voiced in Japanese by Masumi Asano. Asano described Yūka's initial character as a rough and loud person with a kind heart. In the English dub, she is voiced by Martha Harms.
Itsuki Tomofusa (鞘総 逸樹, Tomofusa Itsuki): The class president for Saya's class, he is considered the class' star and has unspoken feelings for Saya that she is oblivious to. He is also part of the experiment, but develops genuine feelings for Saya that lead to his death when he tries to defend her from Fumito's men. It is later revealed that he was a spy sent by enemies of Fumito to observe and report on the experiment. Itsuki is voiced in Japanese by Atsushi Abe. Abe described Itsuki as a distinguished figure who is overly quiet about his feelings. In the English dub, he is voiced by Chris Burnett.
Shinichirō Tokizane (時真 慎一郎, Tokizane Shin'ichirō): A taciturn classmate of Saya for whom she develops a crush during the course of the series. While he feigns affection for Saya, he is in revealed to be a mercenary taking part in the experiment on promise of a high payment. Shinichirō is voiced in Japanese by Tatsuhisa Suzuki. Suzuki defined Shinichirō as a silent character with an air of importance surrounding him. In the English dub, he is voiced by Scott Freeman.
Nene & Nono Motoe (求衛 ねね&のの, Motoe Nene & Nono): A pair of identical twin girls in Saya's class, who act in a mischievous way and often speak in unison. In reality, they are former criminals who participated in the charade to have their records erased so they could find work. The pair are voiced in Japanese by Misato Fukuen. Fukuen described the duo as the anime's "mascot characters". In the English dub, they are voiced by Lindsay Seidel.
Kanako Tsutsutori (筒鳥 香奈子, Tsutsutori Kanako): Saya's homeroom teacher, a woman with a casual and sometimes joking attitude, and a liking for Saya. She is also fascinated by old stories and folklore. In reality, she is a scholar who agreed to participate in Fumito's scheme to learn about Saya and prove the Elder Bairns' existence. Kanako is voiced in Japanese by Miho Miyagawa. In the English dub she is voiced by Lydia Mackay.
Dog (犬, Inu): A character who converses with Saya over the course of the series, being the one responsible for granting her wish to remain herself. Its true identity is the familiar of Kimihiro Watanuki, a character from the manga series xxxHolic. The dog is voiced by Jun Fukuyama in Japanese. When he was recording his dialogue for the series, Fukuyama was surprised that the very last line of the final episode was given to a dog. In the English dub, the dog is voiced by Todd Haberkorn.
