Cisco is a given name, nickname, and surname. The name is derived from Francisco. It may refer to:
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People with the given name
Cisco Adler (born 1978), American rock musician
Cisco McSorley (born 1950), American politician
Cisco Everville
People with the nickname
Francisco Cisco Carlos (born 1940), retired Major League Baseball pitcher
Gilbert Cisco Houston (1918–1961), American folk singer associated with Woody Guthrie
Israel Cisco Oliver (born 1947), American retired Philippine Basketball Association player
People with the surname
Andre Cisco (born 2000), American football player
Galen Cisco (born 1936), American baseball player
Jay Guy Cisco (1844–1922), American Confederate veteran, journalist, diplomat and businessman
Michael Cisco (born 1970), American writer