John Grimes was an Irish-born prelate of the Roman Catholic Church. He served as bishop of Syracuse in New York State from 1912 until his death in 1922. He previously served as coadjutor bishop of Syracuse from 1909 to 1912.
- Occupation
- Catholic priest, Catholic bishop
- Position held
- Roman Catholic Bishop of Syracuse, titular bishop
- Born
- December 18, 1852
- Died
- July 26, 1922
