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Knox County
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Knox County is a county located in the U.S. state of Tennessee. The population was 511,453 as of a 2025 estimate, making it the third-most populous county in Tennessee. Its county seat is Knoxville, which is the third-most populous city in Tennessee. Knox County is included in the Knoxville metropolitan area. The county is located at the geographical center of the Great Valley of East Tennessee. Near the heart of the county is the origin of the Tennessee River, at the confluence of the Holston and French Broad rivers.
Not who you're looking for? Others named Knox County: county in Texas, United States · county in Maine, United States · county in Kentucky, United States · county in Nebraska, United States