Loose is a surname. Notable people with the surname include:
Christian Loose (born 1975), German politician
Emmy Loose (1914–1987), Austrian opera singer
Jacob Loose (1850–1923), American businessman
Julian Loose (born 1985), German footballer
Ralf Loose (born 1963), German footballer and manager
Thomas Loose (born 1964), West-German slalom canoeist
William Loose (1910–1991), American composer
