Martigné-sur-Mayenne (French pronunciation: [maʁtiɲe syʁ majɛn], before 1984: Martigné) is a commune in the Mayenne department in north-western France.
The commune contains the Château de la Motte-Husson, owned by Dick Strawbridge and Angel Adoree, which features in the Channel 4 television series Escape to the Chateau.