Production
Screenwriter Bill Corbett originally pitched the story for SciFi.com, the website for the Sci Fi Channel, which previously aired Mystery Science Theater 3000, where Corbett worked as a writer and actor. The concept was eventually dropped and Corbett, along with other MST3K alumni, instead developed the online mini-series The Adventures of Edward the Less for the site. Corbett later revived the idea for a movie and discussed it with friend and fellow writer Rob Greenberg, who would become his screenwriting partner for the project. Although both writers acknowledged several other "little people inside big people" movies had been made in the past, Corbett thought the aspect of an entire Star Trek like crew operating a human being bore some originality.
During filming, Meet Dave was transferred from Paramount Pictures (which released many of Murphy's early films) to 20th Century Fox (which released both Dr. Dolittle and its sequel).
Meet Dave was written under the title Starship Dave, but studio executives insisted on a title change in part because of the box-office underperformance and critical reception of The Adventures of Pluto Nash, a 2002 science-fiction comedy that also starred Eddie Murphy. Corbett said the executives also wanted the title changed because they felt having any semblance of science-fiction in the title would isolate a large percentage of audiences. Corbett unsuccessfully argued against the new title, which he described as "beyond generic" and said was repetitive of a comedy released earlier in the year called Meet Bill.
Although the project as it was originally conceived appealed to both children and slightly older audiences, the final script aimed for a much more solidly family-based audience. Corbett and Greenberg wrote the original draft and some subsequent drafts and, although they were given the sole writing credit, Corbett said other writers "have romped through the script as well," including one unnamed writer who spent one week adding material after the final draft was submitted. A large amount of improvising and rewriting was also done on the set, and Corbett and Greenberg had little creative control during filming. Corbett said most of the people they worked with were pleasant and some of the notes from the studio were helpful, but that Meet Dave ultimately suffered from a "too-many-cooks thing."
Filming was expected to begin in March 2007. As of early June, they were filming scenes at the Statue of Liberty in New York City. There was also some filming in early 2007 at an elementary school in Pasadena, California.
