Animal and human rights
Portman has long been an advocate for various causes, including animal rights. She became a vegetarian at age eight after witnessing a demonstration of laser surgery on a chicken during a medical conference with her father. She became a vegan in 2009 after reading Jonathan Safran Foer's Eating Animals and later produced a documentary on factory farming systems in the U.S. by the same title. In September 2017, she was recognized for her work on the film by the Environmental Media Association Awards with the Ongoing Commitment Award. She does not wear animal products and has praised animal-friendly products designed by Stella McCartney and Target. In 2007, she launched her own brand of animal-friendly footwear. In 2007, Portman traveled to Rwanda with Jack Hanna to film the documentary Gorillas on the Brink. Portman has been an advocate of environmental causes since childhood, when she joined an environmental song and dance troupe known as World Patrol Kids.
Portman has also supported anti-poverty causes. In 2004 and 2005, she traveled to Uganda, Guatemala, and Ecuador as the Ambassador of Hope for FINCA International, an organization that promotes micro-lending to help finance women-owned businesses in developing countries. In an interview appearing on the PBS program Foreign Exchange with Fareed Zakaria, she discussed microfinance. Host Fareed Zakaria said that he was "generally wary of celebrities with fashionable causes", but included the segment with Portman because "she really knew her stuff". On This Week with George Stephanopoulos in April 2007, Portman discussed her work with FINCA and how it can benefit women and children in Third World countries. In fall-2007, she visited several university campuses, including Harvard, USC, UCLA, UC Berkeley, Stanford, Princeton, New York University, and Columbia, to inspire students with the power of microfinance and to encourage them to join the Village Banking Campaign to help families and communities lift themselves out of poverty.
Portman is a supporter of the Democratic Party, and for the 2004 presidential election she campaigned for Senator John Kerry. Prior to the 2008 presidential election, she supported Senator Hillary Clinton of New York in the Democratic primaries. Portman later campaigned for Senator Barack Obama of Illinois. In a 2008 interview, she also stated: "I even like John McCain. I disagree with his war stance – which is a really big deal – but I think he's a very moral person." In 2010, her activist work and popularity with young people earned her a nomination for VH1's Do Something Awards, which is dedicated to honoring individuals who do good. In 2011, Portman and her then-fiancé Benjamin Millepied were among the signers of a petition to President Obama in support of same-sex marriage. She supported Obama's re-election campaign in 2012.
In 2009, Portman signed a petition that defended Roman Polanski, who was charged with drugging and raping a thirteen-year-old girl in 1977, and has been a fugitive for decades. In February 2018, she expressed regret over signing the petition.
In January 2011, Portman was appointed an ambassador of WE Charity (formerly known as Free The Children), an international charity and educational partner, spearheading their Power of a Girl campaign. She hosted a contest challenging girls in North America to fundraise for one of WE Charity's all-girl schools in Kenya. As incentives for the contest winner, Portman offered the designer Rodarte dress she wore to the premiere of Black Swan, along with tickets to her next film premiere. It was announced in May 2012 that Portman would be working with watch designer Richard Mille to develop a limited-edition timepiece with proceeds supporting WE Charity. During WE Day California 2019 Portman gave a pro vegan speech in front of the student audience, linking vegan lifestyle and feminism. In December 2019, she visited Kenya a second time with WE Charity and spoke with young girls determined to improve their lives through access to education.
In 2006, Portman served as a guest lecturer at Columbia University for a course in terrorism and counterterrorism, where she spoke about her film V for Vendetta. In February 2015, Portman was among other alumni of Harvard University including Robert F. Kennedy Jr., Darren Aronofsky and Susan Faludi who wrote an open letter to the school demanding it divest its $35,900,000,000 endowment from coal, gas, and oil companies. Later that year in May, she spoke at the annual Harvard Class Day to the graduating class of 2015.
In January 2018, Portman donated $50,000 to the Time's Up initiative. She took part in the 2018 Women's March in Los Angeles, where she spoke about the "sexual terrorism" she experienced at age thirteen after the release of her film Léon: The Professional. She told the crowd, "I understood very quickly, even as a 13-year-old, that if I were to express myself sexually I would feel unsafe and that men would feel entitled to discuss and objectify my body to my great discomfort." She drew attention to the MeToo movement, revealing that her first fan letter was a "rape fantasy" from a man and that her local radio station created a countdown until her eighteenth birthday (when she would reach legal age to consent to have intercourse). Portman also added that she avoided roles with kissing scenes and presented herself as "prudish, conservative, nerdy, serious" in an effort to feel that her body was safe and her voice would be heard. During the event, she wore a "Make America Gay Again" hat, a parody of the "Make America Great Again" slogan.
In 2020, Portman endorsed the "defund the police" movement. In 2020, Portman collaborated with JusticeLA to create a public service announcement #SuingToSaveLives about the health of people in L.A. County jails amid the COVID-19 pandemic. Later in 2020, Portman was announced as one of the co-founders and investors in an almost all-female group that was awarded a new franchise in the National Women's Soccer League, the top level of the women's sport in the U.S. The new team, since unveiled as Angel City FC, began play in the 2022 NWSL season.
In September 2023, Portman spoke at an event for the United Nations Spotlight Initiative to eliminate violence against women and girls, where she urged member states to reinvest in the Initiative and ending gender-based violence. In October 2024, she attended the 2024 Ballon d'Or ceremony in Paris, where she presented the award for the best female player.
At the 2026 Sundance Film Festival, she wore "ICE OUT" and "BE GOOD" buttons in support of opposition to actions by U.S. Immigration and Customs Enforcement (ICE), criticizing the government's immigration enforcement policies as "the worst of the worst of humanity" while praising people who organize and support communities in response to injustice.