Nonhelema Hokolesqua (–1786) was an 18th century Shawnee leader and sister of Cornstalk. She was a participant in Pontiac's War and advocated Shawnee neutrality during the American Revolutionary War. Following the war, and despite her support for the United States, Nonhelema's village was attacked. Her husband, Shawnee Chief Moluntha, was killed, and Nonhelema was captured. She died later that year. Born in 1718 into the Chalakatha (Chilliothe) division of the Shawnee nation and spent her early youth in Pennsylvania. Her brother Cornstalk, and her Métis mother Katee accompanied her father Okowellos to the Alabama country in 1725. Their family returned to Pennsylvania within five years. In 1734 she married her first husband, a Chalakatha chief. By 1750 Nonhelema was a Shawnee chief, having significant influence within the Shawnee settlement in Kentucky known as Lower Shawneetown. Nonhelema had three husbands. The first was a Shawnee man. The third was Shawnee Chief Moluntha. She had a son, Thomas McKee, through her relationship with Indian agent Colonel Alexander McKee and another son, Captain Butler/Tamanatha, through her relationship with Colonel Richard Butler. Nonhelema, known as a warrior, stood nearly six feet, six inches (198 cm). Some called her "The Grenadier" or "The Grenadier Squaw", due to the large height of 18th-century grenadiers. She was present at the Battle of Bushy Run in 1763. Nonhelema and Cornstalk supported neutrality when their land became the Western theater of the American Revolutionary War. In Summer 1777, Nonhelema warned Americans that parts of the Shawnee nation had traveled to Fort Detroit to join the British.

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Nonhelema Hokolesqua (–1786) was an 18th century Shawnee leader and sister of Cornstalk. She was a participant in Pontiac's War and advocated Shawnee neutrality during the American Revolutionary War. Following the war, and despite her support for the United States, Nonhelema's village was attacked. Her husband, Shawnee Chief Moluntha, was killed, and Nonhelema was captured. She died later that year.