Shapur Meshanshah (Middle Persian: 𐭱𐭧𐭯𐭥𐭧𐭥𐭩 𐭱𐭠𐭤𐭬𐭩𐭱𐭠𐭭), was a 3rd-century Sasanian prince. He was the second son of the Sassanian shah Shapur I, and was married to a certain queen named Denag, who bore him several children: Hormizd, Hormizdag, Odabakht, Bahram, Shapur, Peroz, and Shapurdukhtak. At an unknown date, Shapur was appointed governor of Meshan by his father. Sometime later, he gave his wife the honorific title of Dastgerd-Shapur. He died in 260, and was probably succeeded by his wife as the governor of Meshan.