Other work
After leaving ER in 1996, Stringfield taught a script analysis class and directed several plays at her alma mater. She took roles in films such as 54 (1998) and Autumn in New York (2000) and appeared in the television movies Border Line (1999) — produced by her ER co-star Anthony Edwards — and Going Home (2000), in which she starred opposite Jason Robards. She also guest-starred in the CBS drama Touched by an Angel in 1999.
In 2005, Stringfield was cast alongside Michael Michele, Blair Underwood, Esai Morales, Gary Cole and Catherine Bell in the pilot episode of the CBS drama Company Town (created by Elwood Reid; directed by Thomas Carter), playing Angie Amberson, a mother of teenagers and a whistle-blower on the investment firm where she works. Company Town failed to get picked up for the 2006 fall season. The series was produced by Jack Clements and Larry Sanitsky. In 2007 Stringfield starred in the Andrew Shea film Forfeit. She played the role of Karen, the ex-girlfriend of a clinical sociopath who schemes and plots to stage a massive robbery and sets Karen up to take the rap.
In 2007, Stringfield guest-starred as attorney Nora March in the CBS drama Shark. She also played a recurring role in the HBO drama Tell Me You Love Me (previously known as Sexlife), which also aired in 2007. In 2009, she appeared in The Stepfather, a remake of the 1987 American thriller film of the same name.
She appeared in an episode of the USA Network drama In Plain Sight. Stringfield also guest-starred on Law & Order in late 2008 as a ruthless court clerk and Michael Cutter's love interest. She also played Mary Jane Porter, an old girlfriend of Larry David's who runs into and then goes on a date with him in an episode of Curb Your Enthusiasm that aired on October 11, 2009.
In 2010, Stringfield appeared in Who Is Clark Rockefeller? playing the role of Sandra Boss.
In addition to acting, Stringfield has done voice-over work, including the voice of Eyeleen in the children's television show Blue's Clues and voicing her ER character for the PC game ER: The Game. Stringfield was also featured in the U.S. Got Milk? advertising campaign, despite being lactose intolerant.
In 2012, Stringfield starred in The Confession, a Hallmark Channel movie and a sequel to The Shunning.
In November 2013, Stringfield guest-starred in the CBS police drama CSI: Crime Scene Investigation in season 14: episode 8 titled "Helpless", playing swing shift CSI Dawn Banks. In 2014, Stringfield played a recurring role on the CBS mystery Under the Dome during its second season.
In 2017, Stringfield appeared on Criminal Minds spinoff, Criminal Minds: Beyond Borders as the wife of Gary Sinise's character, Jack Garrett.