
Place
city in Scott and New Madrid counties in Missouri, United States
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Sikeston is a city located both in southern Scott County and northern New Madrid County, in the state of Missouri, United States. It is situated just north of the "Missouri Bootheel", although many locals consider Sikeston a part of it. By way of Interstate 55, Interstate 57, and U.S. Route 60, Sikeston is close to the halfway point between St. Louis and Memphis, Tennessee and is four hours from Nashville.