Simon Jones Murphy Sr. (April 2, 1815, Windsor, Maine – February 5, 1905 ) was an American businessman.
Murphy was born in Windsor, Maine and was a lumberman there, beginning as a logger on the Penobscot River and working his way up. In 1866, he moved to Michigan and worked in lumber there as well.
Operating out of Detroit, his company logged thousands of acres of Michigan pine forests. Murphy was one of the first millionaires in Detroit.
In 1887, Murphy began wintering in Whittier, California after purchasing the Ramirez Rancho. While there, he was an irrigator, citrus farmer, oilman, and real estate developer.