The Mysterious Miss C. (French: La mystérieuse Mademoiselle C.) is a Canadian children's fantasy-comedy film, directed by Richard Ciupka and released in 2002. The film stars Marie-Chantal Perron as Mademoiselle Charlotte, a quirky supply teacher who transforms the lives of a struggling class of elementary students. The film was adapted from the "Mlle. Charlotte" series of children's novels by Dominique Demers. The film was the sixth highest-grossing Canadian film of 2002.
Demers received a Genie Award nomination for Best Adapted Screenplay at the 23rd Genie Awards. Perron received a Prix Jutra nomination for Best Actress, and Jean-François Bergeron was nominated for Best Editing, at the 5th Jutra Awards.
A sequel, The Incomparable Miss C., was released in 2004.