Cast
Boyd Holbrook as Quentin "Quinn" McKenna, Emily's estranged husband, the father of Rory and an Army Ranger Captain who discovers the existence of the Predators and leads the battle against them.
Trevante Rhodes as "Nebraska" Williams, a former Marine officer who joins in a special Predator-hunting operation headed up by Quinn and becomes his closest ally.
Olivia Munn as Casey Brackett, an evolutionary biologist who joins the crew's mission.
Jacob Tremblay as Rory McKenna, Quinn and Emily's son, who has a form of autism and is bullied in school, but becomes a key player in the fight against the Predators due to his preternatural ability to learn languages.
Keegan-Michael Key as Coyle, a Marine veteran, who teams up with Quinn and Williams to fight the Predators.
Sterling K. Brown as Will Traeger, a government agent and Director of the "Stargazer Project" who jails Quinn, but later needs his help with fighting the Predators.
Thomas Jane as Baxley, a Marine veteran from the Afghanistan and Iraq wars whose Tourette syndrome causes tics and involuntarily swearing (see Tourette syndrome in film). His character was named after Craig R. Baxley, the stunt coordinator of the 1987 film.
Alfie Allen as Lynch, a former Marine who teams with several other outsiders, including Quinn, to stop the human-hunting Predators in suburbia.
Augusto Aguilera as 'Nettles', a former Huey helicopter pilot and religious zealot who has suffered a traumatic brain injury from a crash.
Jake Busey as Sean Keyes, a head Stargazer scientist, the son of Peter Keyes (played by Busey's father Gary Busey in Predator 2).
Yvonne Strahovski as Emily McKenna, Quinn's estranged wife and the mother to Rory.
Other cast members in smaller roles include R. J. Fetherstonhaugh as Agent Church, Peter Shinkoda as Dr. Yamada, Lochlyn Munro as Lieutenant General Marks, Nikolas Dukic as Derek, Gabriel LaBelle as E.J., Niall Matter as Sapir, Mike Dopud as Dupree, and Garry Chalk as a postal worker. The Predators were portrayed in-suit and via motion capture by stuntmen Brian A. Prince and Kyle Strauts, with vocal work by Brian A. Prince.
Françoise Yip has a brief, non-speaking role (credited as ‘Tracking Supervisor’), after previously playing Ms. Yutani in Aliens vs. Predator: Requiem. Stuntwoman Breanna Watkins, in scenes that were filmed but not used, portrayed Ellen Ripley in one alternate ending, and an adult Rebecca "Newt" Jorden in a second alternate ending, meant to tie in to the Alien franchise in which those characters first appeared and set up an Alien vs. Predator-focused sequel film, depicted as having travelled back in time as the "Predator Killer". Edward James Olmos had a supporting role as General Woodhurst, but his scenes were cut due to time constraints.
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