Tusa is a surname, and may refer to:
Arnold Tusa (born 1940), Canadian politician
Emeric Tușa (born 1941), Romanian rower
Frank Tusa (born 1947), American jazz double-bassist and composer
John Tusa (born 1936), British journalist and arts administrator
Rahma Tusa (born 1993), Ethiopian long-distance runner
Sebastiano Tusa (1952–2019), Italian archaeologist and politician
Vincenzo Tusa (1920–2009), Italian archaeologist