Career
In 1983, at Müller's invitation he joined the ensemble of East Berlin's Deutsches Theater, and became its star due to his versatility in comic and serious roles, appearing in productions such as Goethe's Egmont (1986), Ibsen's Peer Gynt and Lessing's Nathan der Weise (Nathan the Wise, 1988). He took the lead role of Hamlet in both Shakespeare's play and Heiner Müller's Die Hamletmaschine (Hamletmachine, 1989). Mühe later said: "Theatre was the only place in the GDR where people weren't lied to. For us actors it was an island. We could dare to criticise." On screen, he co-starred with his second wife Jenny Gröllmann in Herman Zschoche's film Hälfte des Lebens (Half of Life, 1984) about the German lyric poet Friedrich Hölderlin (1770–1843).
Mühe played a leading role in organizing the demonstrations that took place prior to the reunification of Germany. He often gave public readings from Walter Janka's essay Schwierigkeiten mit der Wahrheit (Difficulties with the Truth, 1989) at the Deutsches Theater, before the book was permitted to be published in East Germany. On 4 November 1989, shortly before the fall of the Berlin Wall, in front of half a million people during the Alexanderplatz demonstration, he declared the Communists' monopoly on power to be invalid. In the same year, he became internationally known after playing, next to Armin Mueller-Stahl and Klaus Maria Brandauer, the leading role in Bernhard Wicki's Das Spinnennetz (Spider's Web, based on the expressionist, fragmentary novel of the same name by Austrian writer Joseph Roth) the right-wing lieutenant Lohse who sleeps and murders his way to professional success in the early Weimar Republic following a near fatal injury during the Wilhelmshaven mutiny of 29 October 1918.
After German reunification, he continued to appear in a large number of films, television programmes and theatre productions in Germany and abroad. He proved his ability to take on comic roles in Schtonk! (1991), an Oscar-nominated satire about the Hitler Diaries hoax, and showed his more serious side in Michael Haneke's Benny's Video (1992), Das Schloss (The Castle, 1997) (an adaptation of Kafka's The Castle (1922)) and Funny Games (1997). In the latter film, Mühe and his third wife Susanne Lothar played a husband and wife held captive in their holiday cabin by two psychotic young men who force them to play sadistic "games" with one another.
In the 2000s, Mühe played Nazis in a sequence of films. He portrayed Joseph Goebbels in Goebbels und Geduldig (Goebbels and Geduldig, 2001); Dr. Josef Mengele in Amen. (2002), a film by Costa Gavras; and was to have played Klaus Barbie in an upcoming feature. His last film was the comedy Mein Führer - Die wirklich wahrste Wahrheit über Adolf Hitler (My Führer: The Truly Truest Truth about Adolf Hitler, 2007), in which he played Prof. Adolf Israel Grünbaum, an actor hired to give Hitler lessons.
In 2006, he appeared at the Barbican Arts Centre in London in Zerbombt, Thomas Ostermeier's German production of Sarah Kane's Blasted, playing a middle-aged journalist whose encounter with a young girl leads to pandemonium in a Leeds hotel room.
Mühe was known in Germany for playing the brilliant but eccentric pathologist Dr. Robert Kolmaar in 73 episodes of the forensic crime serial Der letzte Zeuge (The Last Witness, 1998–2007), for which he was awarded the prize for Beste/r Schauspieler/in in einer Serie (Best Actor or Actress in a TV Series) at the Deutscher Fernsehpreis (German Television Awards) in 2005.