Wake Forest University School of Medicine is the medical school of Wake Forest University, with two campuses located in Winston-Salem, North Carolina and Charlotte, North Carolina, United States. It is affiliated with Atrium Health Wake Forest Baptist, the academic medical center whose clinical arm is Atrium Health Wake Forest Baptist. In 2021, U.S. News & World Report ranked Wake Forest School of Medicine 48th best for research in the nation and 80th best for primary care. The School of Medicine also ranks in the top third of U.S. medical schools in funding from the National Institutes of Health (NIH).
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Winston-Salem Campus
History and background
In 1902, the two-year Wake Forest College Medical School was founded on the college campus in Wake Forest, North Carolina. Thirteen students made up the charter medical class. Tuition was $37.50 per term; additional fees were charged for laboratories and student health care.
The Southern Baptist denomination in 1919 began its first planning for a hospital directed primarily at the care of the poor. Applications were received from Raleigh, High Point, Charlotte, Greensboro, Salisbury and Winston-Salem. The Southern Baptists chose Winston-Salem, and an 88-bed hospital opened there in 1923.
In the wake of a 1935 Carnegie Foundation report suggesting the dissolution of two-year medical schools, those schools began to consider alternatives. Meanwhile, the death of Bowman Gray, the president of R.J. Reynolds Tobacco Co. in Winston-Salem, also in 1935, led his family to consider how to best make use of $750,000 that he left to be put toward a community cause. The Gray family decided to offer the money to a medical school willing to relocate to Winston-Salem. After the University of North Carolina rejected a chance to obtain the money because it did not want to leave Chapel Hill, Wake Forest's medical school dean, Coy Cornelius Carpenter, in 1939 helped to forge a deal for the funds. In 1941, Bowman Gray School of Medicine opened on the campus of N.C. Baptist Hospital with 75 students, including 45 freshmen and 30 sophomores.
The rest of Wake Forest University would follow the medical school to Winston-Salem in 1956, in an effort led by the family of R.J. Reynolds.
The school became known for its innovative curriculum and prominent faculty members, including:
Camillo Artom, a renowned Italian biochemistry expert who fled Italy to escape fascism, and who, at Wake Forest, worked with lipids in research on atherosclerosis, among other subjects.
Richard Masland, a professor of psychiatry and neurology who later became director of the National Institute of Neurological Diseases and Blindness. He encouraged faculty to pursue research grants, which helped the school in its push toward research and growth as an academic medical center.
Admissions and rankings
For the entering class of 2021, 10,703 students applied for admission, 504 were interviewed, and 326 were accepted for 145 spots giving rise to a 3% acceptance rate.
Academics and curriculum
The School of Medicine is a member of the Association of American Medical Colleges (AAMC) and is
accredited by the Liaison Committee on Medical Education (LCME), which is jointly sponsored by the Council on Medical Education of the American Medical Association (AMA) and the AAMC.
In 2017, the 'Wake Ready!' curriculum was implemented changing the focus from the traditional 2 preclinical + 2 clinical years of curriculum to three phases. During the first phase, Foundations, which is 18 months in length, basic science courses are integrated with both clinical and patient care organized by systems. Additionally, students learn about bedside clinical skills, bioethics and population health. The second phase, Immersion, is 12 months in length, allows students to rotate through a series of required clerkships in which the students are members of the medical team learning to treat patients in a hospital setting. Students complete 8 weeks of internal medicine, 7 weeks of surgery, 6 weeks of pediatrics, 2 weeks of ambulatory internal medicine, 7 weeks of obstetrics/gynecology & women's health, 4 weeks of family medicine, 4 weeks of psychiatry, 4 weeks of neurology, and 2 weeks of anesthesiology during this time. Additionally, radiology and basic clinical procedures are integrated longitudinally. The last phase, Individualization, is 14 months in length and allows for students to choose their rotations based on their interests and future career plans, including time for research or away rotations at other institutions. Students also have the opportunity to do electives in foreign countries and gain exposure to the differences in care in other countries.
Students do clinical and research work primarily with Wake Forest Baptist Medical Center, Wake Forest Baptist Health—Brenner Children's Hospital, W.G. Hefner Salisbury Veterans Affairs Medical Center and the Virginia Tech-Wake Forest School of Biomedical Engineering and Sciences.
Joint degree programs
The School of Medicine offers, in conjunction with Wake Forest University's Graduate School of Arts and Sciences, a joint M.D./Ph.D. degree from the M.D./Ph.D. Program It also offers a joint M.D./M.A. degree in bioethics.
The joint Ph.D./M.B.A. program was established in 1999 by the Wake Forest University Graduate School of Arts and Sciences and the Schools of Business, with the goal of providing Ph.D. scientists with the opportunity to obtain advanced business training and internship opportunities.
Finally, there is an M.D./M.S. offered in Clinical and Population Translational Sciences through Wake Forest University's Department of Public Health Sciences.
Institutes and centers
Physicians, scientists and students at Wake Forest School of Medicine often work in the research- or education-based institutes and centers affiliated with the school. These include:
Institutes and research-based centers
Childress Institute for Pediatric Trauma
Clinical and Translational Science Institute
Wake Forest Institute for Regenerative Medicine
Brain Tumor Center of Excellence
Center for Biomedical Informatics
Center for Biomolecular Imaging
Center for Cancer Genomics
Center for Diabetes Research
Center for Genomics and Personalized Medicine Research
Center for Integrative Medicine
Center for Worker Health
Comprehensive Cancer Center
Hypertension and Vascular Research Center
Maya Angelou Center for Health Equity
J. Paul Sticht Center on Aging and Rehabilitation
Wake Forest Primate Center
Education and training-based centers
Center for Applied Learning
Student life
Students participate in a number of volunteer and common-interest organizations. Delivering Equal Access to Care (DEAC) is a student-run clinic serving uninsured, low-income residents of Winston-Salem. Oasis is an online magazine that publishes student artistic and literary works. Other student organizations include interest groups that correspond with particular specialties and Wake Forest chapters of the American Medical Association, Student National Medical Association and Operation Smile. Many students also are active in intramural sports organized through the university.
A significant number of students also participate in research, and the Medical Student Research Program funds student research projects during the summer between their first and second years. The School of Medicine also participates in the Albert Schweitzer Fellowship program, with a number of students winning fellowships each year.
Notable faculty and alumni
William Allan, genetics
Anthony Atala, regenerative medicine and urology
Ruth Benca, sleep medicine
Ken Blum, neuropsychopharmacology and genetics
Paul Bucy, neurology and neurosurgery
Coy Cornelius Carpenter, dean
Richard Cytowic, neurology
James Forrester, politician
Dwayne Godwin, neuroscientist and author
Max Gomez, medical reporter
Tinsley Randolph Harrison, internal medicine
Seth C. Hawkins, emergency/wilderness medicine
David L. Heymann, infectious disease
Robert Lanza, regenerative medicine
Thomas T. Mackie, preventative medicine and infectious disease
Thomas Marshburn, astronaut
Jerry Punch, ESPN commentator
Russel J. Reiter, biology of melatonin
Leon S. Robertson, epidemiology
Charlotte campus
As of 2021, Charlotte was the largest city in the United States without a four-year medical school. On April 10, 2019, Wake Forest Baptist Medical Center and Atrium Health announced that the School of Medicine would have a second campus in Charlotte, North Carolina. Preliminary plans for the campus were revealed August 12, 2020. More specific details were revealed in February 2021 including a seven-story tower, and on March 24, 2021, Atrium Health announced a 20-acre Innovation District at Baxter and McDowell Streets in the Midtown neighborhood of Charlotte. The Innovation District, named The Pearl on March 3, 2022, will include the medical school, residential towers, a hotel, and retail and office space. Construction was expected to start in 2022 with the first students attending in 2024.
The medical school campus formally opened June 2, 2025, with 48 students expected to enroll in July. The campus included a 14-story building and more than 700,000 square feet.



