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Researchers Reveal 3D Genome Folding Linked to Alzheimer's Brain Changes
x/university-of-washington
— Jul 23, 2026
Multiple studies from CMU, Pitt, and UW connect Alzheimer's pathology to changes in the genome’s 3D architecture, linking genome folding to gene activity with advanced techniques like GAGE-seq and the Hicformer AI model to map these changes in brain tissue. Additional work highlights age-related genome regulation shifts, including microglial turnover and blood-brain barrier cell decline, alongside a mid-stage drug trial where an anti-tau therapy showed potential to slow cognitive decline, underscoring 3D genome remodeling as a core facet of disease and aging beyond amyloid and tau alone.
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Video: Travis Kelce’s Friends Attempt to Distract Him in Golf by Playing Taylor Swift’s Song
Reporting
— Mar 29, 2024
There was no “Bad Blood” after Travis Kelce’s golf buddies played a Taylor Swift song to throw him off his game. Spoiler alert — it didn’t work. A video shared by former NBA player Chandler Parsons on Instagram story…
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