A fitness coach recommends adequate protein, regular strength training, quality sleep and staying active to help limit age-related muscle loss, which can be compounded by sedentary habits and rapid weight loss on GLP-1 drugs. Separately, researchers found that age-related declines in mitochondrial cardiolipin may contribute to muscle changes, and restoring it partly reversed muscle wasting in mice—an early finding that could point to future treatments.

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cardiolipin

compound from the class of phospholipids

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Experts Share Ways to Preserve Muscle With Age

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About cardiolipin

Cardiolipin is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition. It can also be found in the membranes of most bacteria. The name "cardiolipin" is derived from the fact that it was first found in animal hearts. It was first isolated from the beef heart in the early 1940s by Mary C. Pangborn. In mammalian cells, but also in plant cells, cardiolipin (CL) is found almost exclusively in the inner mitochondrial membrane, where it is essential for the optimal function of numerous enzymes that are involved in mitochondrial energy metabolism.

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