Scientists May Be Able To Stop Brain-Eating Amoeba In Its Tracks Before It Kills You

A microscopic organism with a track record of causing nearly-always fatal infections may finally have met its match in the form of an isolated bacteria compound recently discovered by researchers.

Scientists at the University of California, San Diego extracted a compound from marine bacteria that appears capable of killing strains of Naegleria fowleri, better known as “the brain-eating amoeba,” within hours, according to a new study published on Monday.

“By identifying a compound that is both faster and more selective, we are moving closer to a treatment that can stop the infection before it causes irreversible damage, which could fundamentally change the prognosis for people who contract this parasite,” study author Anjan Debnath, co-director of UC San Diego’s Center for Discovery and Innovation in Parasitic Diseases, said in a statement from the university.

The amoeba boasts a 97 percent kill rate by causing a rare infection in the human brain after entering the body through the nose, migrating to the brain, consuming brain cells and sparking massive inflammation called primary amoebic meningoencephalitis (PAM), the study notes.

While PAM caused by the parasite is exceedingly rare — the Centers for Disease Control and Prevention (CDC) documented only 173 cases in the U.S. from 1937 to 2025 — there is currently “no optimal treatment regimen,” the study says.

The current treatment method approved by the CDC has only successfully treated a dozen people with a confirmed diagnosis worldwide, the study shares. The disease seems to disproportionately affect young children and males, the study said.

“Thus, there is a critical unmet need to find safer and more efficacious drugs to treat this deadly disease and to prevent future deaths of children and young adults,” researchers wrote in the study.