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John Vane

biochemist

John Vane

Farmacólogo inglés (1927-2004)

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About John Vane

Sir John Robert Vane fue un farmacólogo británico que fue instrumental en la comprensión de cómo la aspirina produce efectos de alivio del dolor y antiinflamatorios y su trabajo condujo a nuevos tratamientos para la enfermedad del corazón y los vasos sanguíneos y la introducción de inhibidores de la ECA. Fue galardonado con el Premio Nobel en Fisiología o Medicina en 1982 junto con Sune Bergström y Bengt Samuelsson por "sus descubrimientos sobre prostaglandinas y sustancias biológicamente activas relacionadas".

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Facts from Wikidata (CC0). Image by Unknown authorUnknown author via Wikimedia Commons (CC BY 4.0).

Occupation

biochemist, pharmacologist, university teacher

Citizenship

United Kingdom

Born

March 29, 1927

Died

November 19, 2004

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Related journals

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Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation Cyclooxygenases 1 and 2 Regulatory functions of the vascular endothelium Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis?Queen Mary University of London University of London

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