John Vane

Also known as John Robert Vane, Sir John Robert Vane, John R. Vane

Sir John Robert Vane fue un farmacólogo británico que fue instrumental en la comprensión de cómo la aspirina produce efectos de alivio del dolor y antiinflamatorios y su trabajo condujo a nuevos tratamientos para la enfermedad del corazón y los vasos sanguíneos y la introducción de inhibidores de la ECA. Fue galardonado con el Premio Nobel en Fisiología o Medicina en 1982 junto con Sune Bergström y Bengt Samuelsson por "sus descubrimientos sobre prostaglandinas y sustancias biológicamente activas relacionadas".

Occupation: biochemist, pharmacologist, university teacher
Citizenship: United Kingdom
Born: March 29, 1927
Died: November 19, 2004

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugsknown for An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregationknown for Cyclooxygenases 1 and 2known for Regulatory functions of the vascular endotheliumknown for Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenaseknown for Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysisknown for Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factorknown for Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis?known for Queen Mary University of Londonemployer University of Londonemployer Barts and The London School of Medicine and Dentistryemployer University of Birminghameducated at

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Also known as John Robert Vane, Sir John Robert Vane, John R. Vane

John Vane

John Vane

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